BDBM26631 (5Z)-5-{[4-(propan-2-yl)phenyl]methylidene}-1,3-thiazolidine-2,4-dione::thiazolidine-2,4-dione, 9a

SMILES CC(C)c1ccc(C=C2SC(O)=NC2=O)cc1

InChI Key InChIKey=GXIDNNRIWNVXTL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26631   

TargetSerine/threonine-protein kinase pim-1(Human)
Medical University of South Carolina

LigandPNGBDBM26631((5Z)-5-{[4-(propan-2-yl)phenyl]methylidene}-1,3-th...)
Affinity DataIC50: 40nMpH: 7.0 T: 2°CAssay Description:The primary screen and evaluation of the compounds was conducted using an ATP-depletion assay. Recombinant human Pim kinase was incubated with S6 kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Medical University of South Carolina

LigandPNGBDBM26631((5Z)-5-{[4-(propan-2-yl)phenyl]methylidene}-1,3-th...)
Affinity DataIC50: 1.00E+5nMAssay Description:The primary screen and evaluation of the compounds was conducted using an ATP-depletion assay. Recombinant human Pim kinase was incubated with S6 kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2009
Entry Details Article
PubMed