BDBM26540 (1S,3R)-4-oxo-6-(4-{[2-(pyridin-3-yl)quinolin-4-yl]methoxy}phenyl)-5-azaspiro[2.4]heptane-1-carboxylic acid::carboxylate-spirocyclopropyl compound, 25

SMILES OC(=O)[C@H]1C[C@@]11CC(NC1=O)c1ccc(OCc2cc(nc3ccccc23)-c2cccnc2)cc1

InChI Key InChIKey=HQSSUNUKWAZRMC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26540   

LigandPNGBDBM26540((1S,3R)-4-oxo-6-(4-{[2-(pyridin-3-yl)quinolin-4-yl...)
Affinity DataKi:  3.22E+3nM ΔG°:  -7.41kcal/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2009
Entry Details Article
PubMed