BDBM265250 US9718790, I-1788

SMILES CCn1c(=O)[nH]\c(=N/c2ccc(Oc3ccnc(c3)C(O)=O)cc2)n(Cc2ccc(Cl)cc2)c1=O

InChI Key InChIKey=HQDKXIYLVPUFME-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 265250   

TargetP2X purinoceptor 3(Rat)
Shionogi

US Patent
LigandPNGBDBM265250(US9718790, I-1788)
Affinity DataIC50: 5nMpH: 7.5Assay Description:Rat P2X3 receptor gene (GenBank accession number NM_031075) was expressed in C6BU-1 cell. The cells stably expressing rat P2X3 were seeded in a 96-we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2018
Entry Details
Go to US Patent

TargetP2X purinoceptor 3(Rat)
Shionogi

US Patent
LigandPNGBDBM265250(US9718790, I-1788)
Affinity DataIC50: 59nMpH: 7.5Assay Description:Rat P2X3 receptor gene (GenBank accession number NM_031075) was expressed in C6BU-1 cell. The cells stably expressing rat P2X3 were seeded in a 96-we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2018
Entry Details
Go to US Patent

TargetP2X purinoceptor 3(Human)
Shionogi

US Patent
LigandPNGBDBM265250(US9718790, I-1788)
Affinity DataIC50: 5nMpH: 7.5Assay Description:Stably expressing cell line (C6BU-1 transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded in a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2018
Entry Details
Go to US Patent