BDBM26500 N-[5-({6-[4-(3-hydroxypropyl)phenyl]pyrimidin-4-yl}amino)-2-methylphenyl]methanesulfonamide::aminopyrimidine, 20

SMILES Cc1ccc(Nc2cc(ncn2)-c2ccc(CCCO)cc2)cc1NS(C)(=O)=O

InChI Key InChIKey=RAFREQMBHRNTEE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26500   

TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM26500(N-[5-({6-[4-(3-hydroxypropyl)phenyl]pyrimidin-4-yl...)
Affinity DataIC50: 3.70E+4nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. After the reaction was terminated, the solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed