BDBM26497 N-[5-({6-[4-(dimethylamino)phenyl]pyrimidin-4-yl}amino)-2-methylphenyl]methanesulfonamide::aminopyrimidine, 17

SMILES CN(C)c1ccc(cc1)-c1cc(Nc2ccc(C)c(NS(C)(=O)=O)c2)ncn1

InChI Key InChIKey=RYYWQDKKNIQWAD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26497   

TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM26497(N-[5-({6-[4-(dimethylamino)phenyl]pyrimidin-4-yl}a...)
Affinity DataIC50: 1.50E+4nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. After the reaction was terminated, the solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed