BDBM26489 N-{2-methoxy-5-[(6-phenylpyrimidin-4-yl)amino]phenyl}methanesulfonamide::aminopyrimidine, 10

SMILES COc1ccc(Nc2cc(ncn2)-c2ccccc2)cc1NS(C)(=O)=O

InChI Key InChIKey=RCANHPBTUVMERN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26489   

TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM26489(N-{2-methoxy-5-[(6-phenylpyrimidin-4-yl)amino]phen...)
Affinity DataIC50: 6.90E+4nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. After the reaction was terminated, the solution wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed