BDBM264614 US9718760, C158

SMILES CCCCCCCCCCCCN(S(=O)(=O)c1ccc(O)c(O)c1)S(=O)(=O)c1ccc(O)c(O)c1

InChI Key InChIKey=QQIFSIOQTHCSMR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 264614   

LigandPNGBDBM264614(US9718760, C158)
Affinity DataIC50: 2.60E+3nMpH: 7.4 T: 2°CAssay Description:To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
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TargetPlasminogen activator inhibitor 1/Tissue-type plasminogen activator(Human)
University of Michigan

US Patent
LigandPNGBDBM264614(US9718760, C158)
Affinity DataIC50: 1.44E+3nMT: 2°CAssay Description:PAI-1 inhibitor compounds were dissolved in DMSO to a final concentration of (10-50 mM), depending upon solubility. Compounds were then diluted in ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
Go to US Patent

TargetAntithrombin-III/Prothrombin(Human)
University of Michigan

US Patent
LigandPNGBDBM264614(US9718760, C158)
Affinity DataIC50: 5.47E+5nMT: 2°CAssay Description:PAI-1 inhibitor compounds were dissolved in DMSO to a final concentration of (10-50 mM), depending upon solubility. Compounds were then diluted in ph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
Go to US Patent