BDBM26412 7-[(3,5-dimethoxyphenyl)amino]-5-{[(3-methoxyphenyl)methyl]amino}imidazo[1,2-a]pyrimidine-8-carboxamide::imidazo[1,2-c]pyrimidine-8-carboxamide, 10k

SMILES COc1cccc(CNc2nc(Nc3cc(OC)cc(OC)c3)c(C(N)=O)c3nccn23)c1

InChI Key InChIKey=PSAYAIMNVLJKEM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26412   

TargetTyrosine-protein kinase ZAP-70(Human)
Kissei Pharmaceutical

LigandPNGBDBM26412(7-[(3,5-dimethoxyphenyl)amino]-5-{[(3-methoxypheny...)
Affinity DataIC50: 530nMpH: 7.6 T: 2°CAssay Description:A coupled spectrophotometric assay was used wherein ADP generated by ZAP-70 kinase was converted to ATP by pyruvate kinase (PK), with concomitant pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kissei Pharmaceutical

LigandPNGBDBM26412(7-[(3,5-dimethoxyphenyl)amino]-5-{[(3-methoxypheny...)
Affinity DataIC50: 6.70E+3nMAssay Description:A coupled spectrophotometric assay was used wherein ADP generated by ZAP-70 kinase was converted to ATP by pyruvate kinase (PK), with concomitant pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed