BDBM26411 7-[(3,5-dimethoxyphenyl)amino]-5-{[(4-methoxyphenyl)methyl]amino}imidazo[1,2-a]pyrimidine-8-carboxamide::imidazo[1,2-c]pyrimidine-8-carboxamide, 10j

SMILES COc1ccc(CNc2nc(Nc3cc(OC)cc(OC)c3)c(C(N)=O)c3nccn23)cc1

InChI Key InChIKey=FLXGGVDRCLMNRL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26411   

TargetTyrosine-protein kinase ZAP-70(Human)
Kissei Pharmaceutical

LigandPNGBDBM26411(7-[(3,5-dimethoxyphenyl)amino]-5-{[(4-methoxypheny...)
Affinity DataIC50: 230nMpH: 7.6 T: 2°CAssay Description:A coupled spectrophotometric assay was used wherein ADP generated by ZAP-70 kinase was converted to ATP by pyruvate kinase (PK), with concomitant pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Kissei Pharmaceutical

LigandPNGBDBM26411(7-[(3,5-dimethoxyphenyl)amino]-5-{[(4-methoxypheny...)
Affinity DataIC50: 1.12E+4nMAssay Description:A coupled spectrophotometric assay was used wherein ADP generated by ZAP-70 kinase was converted to ATP by pyruvate kinase (PK), with concomitant pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2009
Entry Details Article
PubMed