BDBM264022 2-[5-[[4-chloro-2- (cyclopropylmethoxy(phenyl] methoxy]pyrazol-1-yl]pyridine- 4-carboxylic acid::US10173996, Example 106::US20240139197, Compound 36::US9604961, Example 106::US9714230, 106::US9908865, Example 106

SMILES OC(=O)c1ccnc(c1)-n1nccc1OCc1ccc(Cl)cc1OCC1CC1

InChI Key InChIKey=CCXBVLGMHSEBLX-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 264022   

TargetLysine-specific demethylase 5A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM264022(2-[5-[[4-chloro-2- (cyclopropylmethoxy(phenyl] met...)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2020
Entry Details
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TargetLysine-specific demethylase 5B(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM264022(2-[5-[[4-chloro-2- (cyclopropylmethoxy(phenyl] met...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2020
Entry Details
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TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM264022(2-[5-[[4-chloro-2- (cyclopropylmethoxy(phenyl] met...)
Affinity DataIC50: 550nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2020
Entry Details
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TargetLysine-specific demethylase 2B(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM264022(2-[5-[[4-chloro-2- (cyclopropylmethoxy(phenyl] met...)
Affinity DataIC50: 5.50E+3nMAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2020
Entry Details
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TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM264022(2-[5-[[4-chloro-2- (cyclopropylmethoxy(phenyl] met...)
Affinity DataIC50: 280nMAssay Description:Inhibition of KDM4C (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM264022(2-[5-[[4-chloro-2- (cyclopropylmethoxy(phenyl] met...)
Affinity DataIC50: 75nMAssay Description:Inhibition of KDM5A (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetLysine-specific demethylase 5B(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM264022(2-[5-[[4-chloro-2- (cyclopropylmethoxy(phenyl] met...)
Affinity DataIC50: 6nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM264022(2-[5-[[4-chloro-2- (cyclopropylmethoxy(phenyl] met...)
Affinity DataIC50: 25nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2024
Entry Details
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TargetLysine-specific demethylase 5B(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM264022(2-[5-[[4-chloro-2- (cyclopropylmethoxy(phenyl] met...)
Affinity DataIC50: 36nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2024
Entry Details
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TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM264022(2-[5-[[4-chloro-2- (cyclopropylmethoxy(phenyl] met...)
Affinity DataIC50: 280nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2024
Entry Details
Go to US Patent