BDBM263592 US10087181, Compound 63::US10285988, Compound 63::US9713612, 63

SMILES Cc1ccc(cn1)-c1ccc2c(NCc3ccc(cc3)-c3ccnc(C)c3)nccc2c1

InChI Key InChIKey=ZUVWXDNOPAWROE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 263592   

TargetProtein Wnt-3a(Human)
Curegenix

US Patent
LigandPNGBDBM263592(US9713612, 63 | US10087181, Compound 63 | US102859...)
Affinity DataIC50: 5nMAssay Description:Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
Go to US Patent

TargetProtein Wnt-3a(Human)
Curegenix

US Patent
LigandPNGBDBM263592(US9713612, 63 | US10087181, Compound 63 | US102859...)
Affinity DataIC50: 5nMAssay Description:NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a luciferase gene driven b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2019
Entry Details
Go to US Patent

TargetProtein Wnt-3a(Human)
Curegenix

US Patent
LigandPNGBDBM263592(US9713612, 63 | US10087181, Compound 63 | US102859...)
Affinity DataIC50: 5nMAssay Description:Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details
Go to US Patent