BDBM26359 (2Z)-3-[(3-chloro-1H-indol-7-yl)amino]-2-cyano-N,N-dimethyl-3-{[(3S)-2-oxo-1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]azepan-3-yl]amino}prop-2-enamide::3-chloroindole compound, 20

SMILES CN(C)C(=O)C(C#N)C(N[C@H]1CCCCN(CC(=O)N2CCCC2)C1=O)=Nc1cccc2c(Cl)c[nH]c12

InChI Key InChIKey=TZGZUYLAZYIPNS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26359   

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM26359((2Z)-3-[(3-chloro-1H-indol-7-yl)amino]-2-cyano-N,N...)
Affinity DataIC50: 2.40nMpH: 7.4 T: 2°CAssay Description:Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed