BDBM263574 6-(3-fluorophenyl)-N-((6-(2-methylpyridin-4-yl)pyridin-3-yl)methyl)isoquinolin-1-amine (Compound No. 3)::US10087181, Compound 3::US10285988, Compound 3::US9713612, 3

SMILES Cc1cc(ccn1)-c1ccc(CNc2nccc3cc(ccc23)-c2cccc(F)c2)cn1

InChI Key InChIKey=JXZNSWDCKVMZNS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 263574   

TargetProtein Wnt-3a(Human)
Curegenix

US Patent
LigandPNGBDBM263574(6-(3-fluorophenyl)-N-((6-(2-methylpyridin-4-yl)pyr...)
Affinity DataIC50: 10nMAssay Description:Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
Go to US Patent

TargetProtein Wnt-3a(Human)
Curegenix

US Patent
LigandPNGBDBM263574(6-(3-fluorophenyl)-N-((6-(2-methylpyridin-4-yl)pyr...)
Affinity DataIC50: 10nMAssay Description:NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a luciferase gene driven b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/17/2019
Entry Details
Go to US Patent

TargetProtein Wnt-3a(Human)
Curegenix

US Patent
LigandPNGBDBM263574(6-(3-fluorophenyl)-N-((6-(2-methylpyridin-4-yl)pyr...)
Affinity DataIC50: 10nMAssay Description:Materials and Methods: NIH3T3 mouse fibroblast cells (American Type Culture Collection, Manassas, Va.) were transfected with a plasmid containing a l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details
Go to US Patent