BDBM263557 US9556150, i-45::cyclopropanesulfonic acid (2-{5- amino-1-[2-chloro-4-(3-cyano- phenoxy)-phenyl]-1h-pyrazole- 4-carbonyl}-1h-indole-5- carbonyl)-amide

SMILES Nc1c(cnn1-c1ccc(Oc2cccc(c2)C#N)cc1Cl)C(=O)c1cc2cc(ccc2[nH]1)C(=O)NS(=O)(=O)C1CC1

InChI Key InChIKey=BDQJOUXQTBMULB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 263557   

TargetTyrosine-protein kinase BTK(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM263557(cyclopropanesulfonic acid (2-{5- amino-1-[2-chloro...)
Affinity DataIC50: 1.70nMpH: 7.15Assay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (F rster/Fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
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