BDBM263539 US9556150, i-27::{5-amino-1-[4-(4-chloro- benzyloxy)-2-methyl-phenyl]- 1h-pyrazol-4-yl}-[5- (morpholine-4-carbonyl)-1h- indol-2-yl]-methanone

SMILES Cc1cc(OCc2ccc(Cl)cc2)ccc1-n1ncc(C(=O)c2cc3cc(ccc3[nH]2)C(=O)N2CCOCC2)c1N

InChI Key InChIKey=HJOAIDTZUYOTOL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 263539   

TargetTyrosine-protein kinase BTK(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM263539({5-amino-1-[4-(4-chloro- benzyloxy)-2-methyl-pheny...)
Affinity DataIC50: 3.70nMpH: 7.15Assay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (F rster/Fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
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