BDBM263537 US9556150, i-25::{5-amino-1-[6-(2,3-difluoro- phenoxy)-2-methoxy-pyridin-3- yl]-1h-pyrazol-4-yl}-[5- (morpholine-4-carbonyl)-1h- indol-2-yl]-methanone

SMILES COc1nc(Oc2cccc(F)c2F)ccc1-n1ncc(C(=O)c2cc3cc(ccc3[nH]2)C(=O)N2CCOCC2)c1N

InChI Key InChIKey=VXSCQLSRUAXZGX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 263537   

TargetTyrosine-protein kinase BTK(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM263537({5-amino-1-[6-(2,3-difluoro- phenoxy)-2-methoxy-py...)
Affinity DataIC50: 74nMpH: 7.15Assay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (F rster/Fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
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