BDBM263524 US9556150, i-12::{5-amino-1-[4-(2,3-difluoro- phenoxy)-phenyl]-1h-pyrazol-4- yl}-[5-(morpholine-4-carbonyl)- 1h-indol-2-yl]-methanone

SMILES Nc1c(cnn1-c1ccc(Oc2cccc(F)c2F)cc1)C(=O)c1cc2cc(ccc2[nH]1)C(=O)N1CCOCC1

InChI Key InChIKey=MPUWAWPEWIXDBP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 263524   

TargetTyrosine-protein kinase BTK(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM263524({5-amino-1-[4-(2,3-difluoro- phenoxy)-phenyl]-1h-p...)
Affinity DataIC50: 13nMpH: 7.15Assay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (F rster/Fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
Go to US Patent