BDBM263518 US9556150, i-6::{2-[5-amino-1-(5-fluoro-2- methyl-4-phenoxy-phenyl)-1h- pyrazole-4-carbonyl]-1h-indol- 5-yl}-morpholin-4-yl-methanone

SMILES Cc1cc(Oc2ccccc2)c(F)cc1-n1ncc(C(=O)c2cc3cc(ccc3[nH]2)C(=O)N2CCOCC2)c1N

InChI Key InChIKey=PYSRXXMVFHPFEL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 263518   

TargetTyrosine-protein kinase BTK(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM263518({2-[5-amino-1-(5-fluoro-2- methyl-4-phenoxy-phenyl...)
Affinity DataIC50: 43nMpH: 7.15Assay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (F rster/Fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
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