BDBM263516 US9556150, i-4::[5-amino-1-(3-fluoro-4- phenoxy-phenyl)-1h-pyrazol-4- yl]-[5-(morpholine-4-carbonyl)- 1h-indol-2-yl]-methanone

SMILES Nc1c(cnn1-c1ccc(Oc2ccccc2)c(F)c1)C(=O)c1cc2cc(ccc2[nH]1)C(=O)N1CCOCC1

InChI Key InChIKey=NSEDUGIZFVIBTI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 263516   

TargetTyrosine-protein kinase BTK(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM263516([5-amino-1-(3-fluoro-4- phenoxy-phenyl)-1h-pyrazol...)
Affinity DataIC50: 12nMpH: 7.15Assay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (F rster/Fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
Go to US Patent