BDBM263513 US9556150, i-1::[5-amino-1-(4-phenoxy-phenyl)- 1h-pyrazol-4-yl]-[5-(morpholine- 4-carbonyl)-1h-indol-2-yl]- methanone

SMILES Nc1c(cnn1-c1ccc(Oc2ccccc2)cc1)C(=O)c1cc2cc(ccc2[nH]1)C(=O)N1CCOCC1

InChI Key InChIKey=GKEJAWPZSHGAMG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 263513   

TargetTyrosine-protein kinase BTK(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM263513([5-amino-1-(4-phenoxy-phenyl)- 1h-pyrazol-4-yl]-[5...)
Affinity DataIC50: 6.80nMpH: 7.15Assay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (F rster/Fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2018
Entry Details
Go to US Patent