BDBM263022 (S)-2-amino-N-(5H-chromeno[3,4-c]pyridin-8-yl)-2-phenylacetamide::US9663529, Example I-7::US9708337, 36

SMILES N[C@H](C(=O)Nc1ccc-2c(OCc3cnccc-23)c1)c1ccccc1

InChI Key InChIKey=CGXOKVWAHQLXGW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 263022   

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM263022((S)-2-amino-N-(5H-chromeno[3,4-c]pyridin-8-yl)-2-p...)
Affinity DataIC50: 8.90nMpH: 7.4 T: 2°CAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2018
Entry Details
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TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM263022((S)-2-amino-N-(5H-chromeno[3,4-c]pyridin-8-yl)-2-p...)
Affinity DataIC50: 21.8nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2019
Entry Details
Go to US Patent