BDBM262997 N-(5H-chromeno[3,4-c]pyridin-8-yl)-3-isopropylpiperidine-2-carboxamide::US9708337, 10

SMILES CC(C)C1CCCNC1C(=O)Nc1ccc-2c(OCc3cnccc-23)c1

InChI Key InChIKey=FWJOCWBMXPURGY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 262997   

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM262997(N-(5H-chromeno[3,4-c]pyridin-8-yl)-3-isopropylpipe...)
Affinity DataIC50: 1.30nMpH: 7.4 T: 2°CAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2018
Entry Details
Go to US Patent