BDBM26200 N-(1H-indazol-5-yl)-5-methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrazole-3-carboxamide::pyrazolecarboxamide, 4

SMILES Cc1cc(nn1-c1cccc(c1)C(F)(F)F)C(=O)Nc1ccc2[nH]ncc2c1

InChI Key InChIKey=JVZLCCIDXABHFQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26200   

TargetTyrosine-protein kinase JAK3(Human)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM26200(N-(1H-indazol-5-yl)-5-methyl-1-[3-(trifluoromethyl...)
Affinity DataIC50: 2.64E+3nMpH: 7.5 T: 2°CAssay Description:An ELISA assay was used to determine the ability of inhibitor to inhibit JAK3 RTK activity. The compounds were incubated with enzyme, 10 uM ATP, and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2008
Entry Details Article
PubMed