BDBM261736 1-fluoro-N- ((1SR,2RS)-2- hydroxy-2- methylcyclohexyl)- 4-((6-(1-methyl-1H- pyrazol-4-yl)pyridin- 3-yl)methyl)-2- naphthamide::US9708302, 22

SMILES Cn1cc(cn1)-c1ccc(Cc2cc(C(=O)N[C@H]3CCCC[C@@]3(C)O)c(F)c3ccccc23)cn1

InChI Key InChIKey=DQZKNHZVLILHDP-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 261736   

TargetMuscarinic acetylcholine receptor M1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM261736(1-fluoro-N- ((1SR,2RS)-2- hydroxy-2- methylcyclohe...)
Affinity DataEC50:  20nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM261736(1-fluoro-N- ((1SR,2RS)-2- hydroxy-2- methylcyclohe...)
Affinity DataEC50:  41nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
Go to US Patent