BDBM261726 4-(4-chlorobenzyl)- 1-fluoro-N- ((3RS,4SR)-3- hydroxytetrahydro- 2H-pyran-4-yl)-2- naphthamide::US9708302, 12

SMILES O[C@H]1COCC[C@@H]1NC(=O)c1cc(Cc2ccc(Cl)cc2)c2ccccc2c1F

InChI Key InChIKey=PPESFTAATAFJTR-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 261726   

TargetMuscarinic acetylcholine receptor M1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM261726(4-(4-chlorobenzyl)- 1-fluoro-N- ((3RS,4SR)-3- hydr...)
Affinity DataEC50:  152nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
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TargetMuscarinic acetylcholine receptor M1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM261726(4-(4-chlorobenzyl)- 1-fluoro-N- ((3RS,4SR)-3- hydr...)
Affinity DataEC50:  273nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
Go to US Patent