BDBM261723 4-((6-chloropyridin-3- yl)methyl)-1-fluoro-N- ((1SR,2RS)-2- hydroxycyclohexyl)-2- naphthamide::US9708302, 9

SMILES O[C@@H]1CCCC[C@@H]1NC(=O)c1cc(Cc2ccc(Cl)nc2)c2ccccc2c1F

InChI Key InChIKey=ODFVXVSVXQOSMG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 261723   

TargetMuscarinic acetylcholine receptor M1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM261723(4-((6-chloropyridin-3- yl)methyl)-1-fluoro-N- ((1S...)
Affinity DataEC50:  539nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
Go to US Patent