BDBM261718 4-((6-Chloropyridin-3-yl)methyl)-1-fluoro-N-((3S,4S)-4-hydroxytetrahydro-2H-pyran-3-yl)-2-naphthamide::US9708302, 4

SMILES O[C@H]1CCOC[C@@H]1NC(=O)c1cc(Cc2ccc(Cl)nc2)c2ccccc2c1F

InChI Key InChIKey=OCZBYPSETUGCDU-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 261718   

TargetMuscarinic acetylcholine receptor M1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM261718(4-((6-Chloropyridin-3-yl)methyl)-1-fluoro-N-((3S,4...)
Affinity DataEC50:  428nMAssay Description:The assay is designed to select compounds that possess modulator activity at the acetylcholine muscarinic receptor expressed in CHO cells by measurin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
Go to US Patent