BDBM261688 (R)-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-4'-methoxy-1 ,2 ,3 ,6 -tetrahydro-[3,3':6',4 -terpyridin]-6-amine::US9708295, 29

SMILES COc1cc(ncc1-c1cnc(N)c(O[C@H](C)c2c(Cl)ccc(I)c2Cl)c1)C1=CCNCC1

InChI Key InChIKey=SYRNZMNLJVMENP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 261688   

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM261688((R)-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-4'-m...)
Affinity DataIC50: 19.2nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent