BDBM261588 US10513499, Compound 11::US11254644, Compound 11::US9708272, 11

SMILES OC(=O)c1cccc(CSc2nc(-c3ccccc3)c(Br)c(=O)[nH]2)c1

InChI Key InChIKey=IIWWWULREDJDGH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 261588   

LigandPNGBDBM261588(US9708272, 11 | US10513499, Compound 11 | US112546...)
Affinity DataIC50: 71nMAssay Description:The pre-assay mixture consisting of 3-hydroxyanthranilic acid (3OH-HA), 3-hydroxyanthranilic acid, 3,4-diOxygenase (HAO), and a dialyzed crude extrac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

LigandPNGBDBM261588(US9708272, 11 | US10513499, Compound 11 | US112546...)
Affinity DataIC50: 99nMAssay Description:Inhibition of human ACMSD expressed in Pichia pastoris using ACMS as substrate by coupled spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2019
Entry Details Article
PubMed
LigandPNGBDBM261588(US9708272, 11 | US10513499, Compound 11 | US112546...)
Affinity DataIC50: 71nMAssay Description:The pre-assay mixture consisting of 3-hydroxyanthranilic acid (30H-HA), 3-hydroxyanthranilic acid, 3,4-diOxygenase (HAO), and a dialyzed crude extrac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2020
Entry Details
Go to US Patent

LigandPNGBDBM261588(US9708272, 11 | US10513499, Compound 11 | US112546...)
Affinity DataIC50: 71nMAssay Description:The activity of compounds 1-19 and 21-23 as inhibitors of ACMSD1 was determined by measuring the conversion of 3OH-Anthranilic Acid into product (i.e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2022
Entry Details
Go to US Patent