BDBM261480 US10011568, Ex. No. 3::US9708266, 3

SMILES CN(C(=O)C(C)(C)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1cnc(cc1-c1ccc(F)cc1C)C1CCCC(CC(O)=O)C1

InChI Key InChIKey=HENCBHAKHZDBGT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 261480   

TargetSubstance-P receptor(Human)
Kissei Pharmaceutical

US Patent
LigandPNGBDBM261480(US9708266, 3 | US10011568, Ex. No. 3)
Affinity DataIC50: 2.10nMpH: 7.4 T: 2°CAssay Description:The buffer solution for the receptor binding test was dispensed to the wells of a 96-well assay plate (Greiner) at 22.5 μL/well. DMSO solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Kissei Pharmaceutical

US Patent
LigandPNGBDBM261480(US9708266, 3 | US10011568, Ex. No. 3)
Affinity DataIC50: 9.40E+3nMpH: 7.4 T: 2°CAssay Description:A dimethyl sulfoxide (DMSO) solution of a test compound with a concentration 1000 times higher than the evaluation concentration was prepared, and a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

TargetSubstance-P receptor(Human)
Kissei Pharmaceutical

US Patent
LigandPNGBDBM261480(US9708266, 3 | US10011568, Ex. No. 3)
Affinity DataIC50: 2.10nMAssay Description:The buffer solution for the receptor binding test was dispensed to the wells of a 96-well assay plate (Greiner) at 22.5 μL/well. DMSO solutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Kissei Pharmaceutical

US Patent
LigandPNGBDBM261480(US9708266, 3 | US10011568, Ex. No. 3)
Affinity DataIC50: 9.40E+3nMAssay Description:A dimethyl sulfoxide (DMSO) solution of a test compound with a concentration 1000 times higher than the evaluation concentration was prepared, and a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2020
Entry Details
Go to US Patent