BDBM26125 3-(dihydroxyboranyl)benzonitrile::Phenylboronic Acid, 4

SMILES OB(O)c1cccc(c1)C#N

InChI Key InChIKey=XDBHWPLGGBLUHH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 26125   

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Oxford

LigandPNGBDBM26125(3-(dihydroxyboranyl)benzonitrile | Phenylboronic A...)
Affinity DataIC50: 1.60E+3nMpH: 7.4 T: 2°CAssay Description:[3H]Ethanolamine produced from [3H]AEA hydrolysis was used to calculate FAAH activity and was measured by scintillation counting of the aqueous phase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Oxford

LigandPNGBDBM26125(3-(dihydroxyboranyl)benzonitrile | Phenylboronic A...)
Affinity DataAssay Description:[3H]Ethanolamine produced from [3H]AEA hydrolysis was used to calculate FAAH activity and was measured by scintillation counting of the aqueous phase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
TargetAutotaxin(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM26125(3-(dihydroxyboranyl)benzonitrile | Phenylboronic A...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as substrate preincubated for 20 mins followed by substrate addition by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed