BDBM261187 5-[1-(4-Amino-3-methyl-1H- pyrazolo[3,4-d]pyrimidin-1- yl)ethyl]-4-ethoxy-2-methyl-3-(1- methyl-1H-pyrazol-4- yl)benzonitrile3::US11433071, Example 210::US9707233, 210

SMILES CCOc1c(cc(C#N)c(C)c1-c1cnn(C)c1)C(C)Nc1ncnc(N)c1C(C)=N

InChI Key InChIKey=DKPDDCVWWZLCGE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 261187   

LigandPNGBDBM261187(5-[1-(4-Amino-3-methyl-1H- pyrazolo[3,4-d]pyrimidi...)
Affinity DataIC50: 10nMpH: 6.7 T: 2°CAssay Description:Lipid kinase substrate, phosphoinositol-4,5-bisphosphate (PIP2), are purchased from Echelon Biosciences (Salt Lake City, Utah). PI3K isoforms α,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
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LigandPNGBDBM261187(5-[1-(4-Amino-3-methyl-1H- pyrazolo[3,4-d]pyrimidi...)
Affinity DataIC50: 10nMAssay Description:The kinase reaction was conducted in polystyrene 384-well matrix white plate from Thermo Fisher Scientific in a final volume of 25 μL. Inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2022
Entry Details
Go to US Patent