BDBM261163 1-(1-(5-chloro-3-(2- (dimethylamino)pyridin-4-yl)-2- methoxy-4-methylphenyl)ethyl)-3- methyl-1H-pyrazolo[3,4- d]pyrimidin-4-amine3::US9707233, 186

SMILES COc1c(cc(Cl)c(C)c1-c1cncc(c1)N(C)C)C(C)Nc1ncnc(N)c1C(C)=N

InChI Key InChIKey=XEHLEMDXSBOSME-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 261163   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta/delta isoform(Human)
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US Patent

LigandBDBM261163(1-(1-(5-chloro-3-(2- (dimethylamino)pyridin-4-yl)-...)Copy SMILESCopy InChI

Affinity DataIC50: 10nMpH: 6.7 T: 2°CAssay Description:Lipid kinase substrate, phosphoinositol-4,5-bisphosphate (PIP2), are purchased from Echelon Biosciences (Salt Lake City, Utah). PI3K isoforms α,...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/30/2018
Entry Details
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