BDBM26064 2-benzyl-3-aryl-7-trifluoromethylindazole, 5::2-benzyl-3-phenyl-7-(trifluoromethyl)-2H-indazole

SMILES FC(F)(F)c1cccc2c(-c3ccccc3)n(Cc3ccccc3)nc12

InChI Key InChIKey=LGRUCHCYEMOENE-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26064   

TargetOxysterols receptor LXR-beta [154-461](Human)
Wyeth Research

LigandPNGBDBM26064(2-benzyl-3-phenyl-7-(trifluoromethyl)-2H-indazole ...)
Affinity DataIC50: 41nM EC50:  3.26E+3nMpH: 7.4 T: 2°CAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha [197-447](Human)
Wyeth Research

LigandPNGBDBM26064(2-benzyl-3-phenyl-7-(trifluoromethyl)-2H-indazole ...)
Affinity DataIC50: 279nM EC50:  4.27E+3nMAssay Description:Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed