BDBM260620 US10098900, Compound 5::US10300066, Compound 94::US9532990, 94::US9717745, 5

SMILES Nc1ncnc2n(nc(-c3ccc(Oc4cccc(F)c4)cc3F)c12)[C@@H]1CCN(C1)C(=O)C=C

InChI Key InChIKey=QLRDEQPODCORHJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 260620   

TargetTyrosine-protein kinase BTK(Human)
Zhejiang Dtrm Biopharma

US Patent
LigandPNGBDBM260620(US9532990, 94 | US9717745, 5 | US10098900, Compoun...)
Affinity DataIC50: 1nMT: 2°CAssay Description:The enzyme reaction mixture of BTK wild type standard HTRF assay contained 1 nM BTK wild type, 1 μM biotin-TK1 peptide, and 30 μM ATP in a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2017
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Zhejiang Dtrm Biopharma

US Patent
LigandPNGBDBM260620(US9532990, 94 | US9717745, 5 | US10098900, Compoun...)
Affinity DataIC50: 1nMT: 2°CAssay Description:The enzyme reaction mixture of BTK wild type standard HTRF assay contained 1 nM BTK wild type, 1 μM biotin-TK1 peptide, and 30 μM ATP in a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Zhejiang Dtrm Biopharma

US Patent
LigandPNGBDBM260620(US9532990, 94 | US9717745, 5 | US10098900, Compoun...)
Affinity DataIC50: 1nMT: 2°CAssay Description:The enzyme reaction mixture of BTK wild type standard HTRF assay contained 1 nM BTK wild type, 1 μM biotin-TK1 peptide, and 30 μM ATP in a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Zhejiang Dtrm Biopharma

US Patent
LigandPNGBDBM260620(US9532990, 94 | US9717745, 5 | US10098900, Compoun...)
Affinity DataIC50: 6nMAssay Description:The enzyme reaction mixture of BTK wild type standard HTRF assay contained 1 nM BTK wild type, 1 μM biotin-TK1 peptide, and 30 μM ATP in a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Zhejiang Dtrm Biopharma

US Patent
LigandPNGBDBM260620(US9532990, 94 | US9717745, 5 | US10098900, Compoun...)
Affinity DataIC50: 1nMAssay Description:The enzyme reaction mixture of BTK wild type standard HTRF assay contained 1 nM BTK wild type, 1 μM biotin-TK1 peptide, and 30 μM ATP in a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
Go to US Patent