BDBM260617 US10300066, Compound 91::US9532990, 91

SMILES CN(C)C\C=C\C(=O)N1CC[C@H](C1)n1nc(-c2ccc(Oc3c(F)c(F)cc(F)c3F)cc2F)c2c(N)ncnc12

InChI Key InChIKey=GZCDJPFVLMKCQJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 260617   

TargetTyrosine-protein kinase BTK(Human)
Zhejiang Dtrm Biopharma

US Patent
LigandPNGBDBM260617(US9532990, 91 | US10300066, Compound 91)
Affinity DataIC50: 3nMT: 2°CAssay Description:The enzyme reaction mixture of BTK wild type standard HTRF assay contained 1 nM BTK wild type, 1 μM biotin-TK1 peptide, and 30 μM ATP in a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2017
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Zhejiang Dtrm Biopharma

US Patent
LigandPNGBDBM260617(US9532990, 91 | US10300066, Compound 91)
Affinity DataIC50: 3nMAssay Description:The enzyme reaction mixture of BTK wild type standard HTRF assay contained 1 nM BTK wild type, 1 μM biotin-TK1 peptide, and 30 μM ATP in a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
Go to US Patent