BDBM260546 US10300066, Compound 20::US9532990, 20

SMILES CS(=O)(=O)Nc1cccc(Oc2ccc(-c3nn(C4CCCN(C4)C(=O)C=C)c4ncnc(N)c34)c(F)c2)c1

InChI Key InChIKey=HUTZJNUJLUQXGI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 260546   

TargetTyrosine-protein kinase BTK(Human)
Zhejiang Dtrm Biopharma

US Patent
LigandPNGBDBM260546(US9532990, 20 | US10300066, Compound 20)
Affinity DataIC50: 4nMT: 2°CAssay Description:The enzyme reaction mixture of BTK wild type standard HTRF assay contained 1 nM BTK wild type, 1 μM biotin-TK1 peptide, and 30 μM ATP in a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2017
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Zhejiang Dtrm Biopharma

US Patent
LigandPNGBDBM260546(US9532990, 20 | US10300066, Compound 20)
Affinity DataIC50: 4nMAssay Description:The enzyme reaction mixture of BTK wild type standard HTRF assay contained 1 nM BTK wild type, 1 μM biotin-TK1 peptide, and 30 μM ATP in a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
Go to US Patent