BDBM260531 US10300066, Compound 5::US9532990, 5

SMILES Nc1ncnc2n(nc(-c3ccc(cc3F)C(=O)c3cccc(F)c3)c12)C1CCCN(C1)C(=O)C=C

InChI Key InChIKey=OOXOANBXOYMTTA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 260531   

TargetTyrosine-protein kinase BTK(Human)
Zhejiang Dtrm Biopharma

US Patent
LigandPNGBDBM260531(US9532990, 5 | US10300066, Compound 5)
Affinity DataIC50: 2nMT: 2°CAssay Description:The enzyme reaction mixture of BTK wild type standard HTRF assay contained 1 nM BTK wild type, 1 μM biotin-TK1 peptide, and 30 μM ATP in a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2017
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Zhejiang Dtrm Biopharma

US Patent
LigandPNGBDBM260531(US9532990, 5 | US10300066, Compound 5)
Affinity DataIC50: 2nMAssay Description:The enzyme reaction mixture of BTK wild type standard HTRF assay contained 1 nM BTK wild type, 1 μM biotin-TK1 peptide, and 30 μM ATP in a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2020
Entry Details
Go to US Patent