BDBM260413 US9527838, 41

SMILES CCOC(=O)Cc1nc(NC(=O)c2nc(Sc3nncn3C)ccc2Sc2ccc(cc2)C(F)(F)F)sc1Cl

InChI Key InChIKey=YNNKIQBVTLSYSN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 260413   

TargetHexokinase-4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM260413(US9527838, 41)
Affinity DataEC50:  18.9nMAssay Description:Recombinant human liver glucokinase was expressed as a FLAG fusion protein in E. coli, and purified on ANTIFLAG M2 AFFINITY GEL (Sigma). The assay wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2017
Entry Details
Go to US Patent