BDBM2600 (Arylindolyl)maleimide deriv. 22::3-(1-benzofuran-3-yl)-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione::CHEMBL301138

SMILES Cn1cc(C2=C(C(=O)NC2=O)c2coc3ccccc23)c2ccccc12

InChI Key InChIKey=KCBBKYDLIADLOS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 2600   

TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2600(3-(1-benzofuran-3-yl)-4-(1-methyl-1H-indol-3-yl)-2...)
Affinity DataIC50: 2.60E+3nMAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2004
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM2600(3-(1-benzofuran-3-yl)-4-(1-methyl-1H-indol-3-yl)-2...)
Affinity DataIC50: 35nMAssay Description:Inhibition of human GSK3-beta by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM2600(3-(1-benzofuran-3-yl)-4-(1-methyl-1H-indol-3-yl)-2...)
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of CDK2/Cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM2600(3-(1-benzofuran-3-yl)-4-(1-methyl-1H-indol-3-yl)-2...)
Affinity DataIC50: 35nMAssay Description:Inhibition of GSK-3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed