BDBM259830 US9505766, 34

SMILES CNC(=O)C(=C\c1ccc2[nH]ncc2c1)\C#N

InChI Key InChIKey=RQRJOTZDZIGRHX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 259830   

TargetRibosomal protein S6 kinase alpha-3 [399-740](Human)
University of California

US Patent
LigandPNGBDBM259830(US9505766, 34)
Affinity DataIC50: 129nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2017
Entry Details
Go to US Patent