BDBM259823 US9505766, 24

SMILES NC(=O)C(=C\c1ccc(cc1)-c1cn[nH]c1)\C#N

InChI Key InChIKey=BNRLLVUNYCBXNJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 259823   

TargetRibosomal protein S6 kinase alpha-3 [399-740](Human)
University of California

US Patent
LigandPNGBDBM259823(US9505766, 24)
Affinity DataIC50: 5.00E+3nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2017
Entry Details
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TargetRibosomal protein S6 kinase alpha-3 [399-740,C436V](Human)
University of California

US Patent
LigandPNGBDBM259823(US9505766, 24)
Affinity DataIC50: 1.50E+5nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2017
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase PLK1(Human)
University of California

US Patent
LigandPNGBDBM259823(US9505766, 24)
Affinity DataIC50: 1.00E+4nMpH: 7.6 T: 2°CAssay Description:Human PLK1 (Millipore, catalog number 14-777M) (7.2 nM) in 20 mM Hepes, pH 7.6, 10 mM MgCl2, 1 mM EDTA, 0.2 mg/mL BSA, and 100 μM ATP was pre-in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2017
Entry Details
Go to US Patent