BDBM25945 8-methoxy-12-methyl-4-phenyl-3-thia-1,7,10-triazatricyclo[7.3.0.0^{2,6}]dodeca-2(6),4,7,9,11-pentaene::imidazothienopyrazine, 18

SMILES COc1nc2cc(sc2n2c(C)cnc12)-c1ccccc1

InChI Key InChIKey=ROCPTTVMVKUQNN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 25945   

LigandPNGBDBM25945(8-methoxy-12-methyl-4-phenyl-3-thia-1,7,10-triazat...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2008
Entry Details Article
PubMed
LigandPNGBDBM25945(8-methoxy-12-methyl-4-phenyl-3-thia-1,7,10-triazat...)
Affinity DataIC50: 1.00E+3nMAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2008
Entry Details Article
PubMed
LigandPNGBDBM25945(8-methoxy-12-methyl-4-phenyl-3-thia-1,7,10-triazat...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human IKK-beta using TMB as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed