BDBM259297 US9499547, 38

SMILES COc1ccc2oc(cc2c1)-c1cnc2ccc(O[C@H]3C[C@H](N)C3)nn12

InChI Key InChIKey=BTQWZDHVYFAXAO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 259297   

LigandPNGBDBM259297(US9499547, 38)
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
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LigandPNGBDBM259297(US9499547, 38)
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:MKNK1-inhibitory activity at high ATP of compounds of the present invention after their preincubation with MKNK1 was quantified employing the TR-FRET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
Go to US Patent