BDBM25928 N-(2-aminoethyl)-12-methyl-3-thia-1,7,10-triazatricyclo[7.3.0.0^{2,6}]dodeca-2(6),4,7,9,11-pentaen-8-amine::imidazothienopyrazine, 13a

SMILES Cc1cnc2c(NCCN)nc3ccsc3n12

InChI Key InChIKey=NSSAAAYFAVFGIU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 25928   

LigandPNGBDBM25928(N-(2-aminoethyl)-12-methyl-3-thia-1,7,10-triazatri...)
Affinity DataIC50: 1.21E+4nMpH: 7.5 T: 2°CAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2008
Entry Details Article
PubMed
LigandPNGBDBM25928(N-(2-aminoethyl)-12-methyl-3-thia-1,7,10-triazatri...)
Affinity DataIC50: 170nMAssay Description:Assays measuring the enzyme-catalyzed phosphorylation of GST-I kappa B alpha were performed. The phosphorylated substrate was detected using a Phosph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2008
Entry Details Article
PubMed
LigandPNGBDBM25928(N-(2-aminoethyl)-12-methyl-3-thia-1,7,10-triazatri...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human IKK-beta using TMB as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed