BDBM258871 US9499492, 23

SMILES C[S@@](=O)(Cc1cc(Nc2ncc(F)c(n2)-c2ccc(F)cc2F)cc(c1)C(F)(F)F)=NC(N)=O

InChI Key InChIKey=QQOSANNDIZSJOV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 258871   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM258871(US9499492, 23)
Affinity DataIC50: 4nMpH: 8.0 T: 2°CAssay Description:Method 1a: Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/Glutathione S-transferase P(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM258871(US9499492, 23)
Affinity DataIC50: 370nMpH: 8.0 T: 2°CAssay Description:Method 2: Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
Go to US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM258871(US9499492, 23)
Affinity DataIC50: 16nMpH: 8.0 T: 2°CAssay Description:Method 1b: Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were pu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
Go to US Patent