BDBM258291 US9493485, 9-132

SMILES C[C@]1(CC2(CCC(F)(F)CC2)OC(N)=N1)c1cc(NC(=O)c2ccc(cn2)C(F)(F)F)ccc1F

InChI Key InChIKey=LDVLXRCSXITKMQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 258291   

TargetBeta-secretase 1(Human)
Imago Pharmaceuticals

US Patent
LigandPNGBDBM258291(US9493485, 9-132)
Affinity DataIC50: 6nMpH: 7.0Assay Description:BACE1 activity can be assessed in an AlphaScreen assay. Compounds to be assessed (e.g. compounds as described in the above examples) are serially dil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2017
Entry Details
Go to US Patent