BDBM258249 BDBM363077::US9493448, 158::US9597330, Example 59

SMILES Fc1cc(O[C@H]2CCCC[C@@H]2c2ccn[nH]2)c(Cl)cc1S(=O)(=O)Nc1ccncn1

InChI Key InChIKey=ZISLEKLOYZSQNE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 258249   

TargetSodium channel protein type 9 subunit alpha(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM258249(US9493448, 158 | US9597330, Example 59 | BDBM36307...)
Affinity DataIC50: 28nMpH: 7.3 T: 2°CAssay Description:Current record was obtained by an automated patch clamp system IonWorks Quattro (Molecular Devices Corporation) in Population Patch Clamp mode. The o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2017
Entry Details
Go to US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM258249(US9493448, 158 | US9597330, Example 59 | BDBM36307...)
Affinity DataIC50: 28nMAssay Description:Current recording was obtained by an automated patch clamp system IonWorks Quattro (Molecular Devices Corporation) in Population Patch Clamp mode. Th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM258249(US9493448, 158 | US9597330, Example 59 | BDBM36307...)
Affinity DataIC50: 28nMAssay Description:Current record was obtained by an automated patch clamp system IonWorks Quattro (Molecular Devices Corporation) in Population Patch Clamp mode. The o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
Go to US Patent