BDBM257507 US9505736, (1R,2S,3S)-2-(4-(2-Cyclopropyloxazol- 5-yl)phenyl)-1-fluoro-N-hydroxy-3- phenylcyclopropanecarboxamide

SMILES ONC(=O)[C@@]1(F)[C@@H]([C@H]1c1ccc(cc1)-c1cnc(o1)C1CC1)c1ccccc1

InChI Key InChIKey=FZFWDBNDYFWRRQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 257507   

TargetHistone deacetylase 4 [648-729,745-1057](Human)
Chdi Foundation

US Patent
LigandPNGBDBM257507(US9505736, (1R,2S,3S)-2-(4-(2-Cyclopropyloxazol- 5...)
Affinity DataIC50: 4.65E+3nMpH: 8.0 T: 2°CAssay Description:The potency of Class IIa Histone Deacetylase (HDAC) inhibitors is quantified by measuring the Histone Deacetylase 4 (HDAC4) catalytic domain enzymati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2017
Entry Details
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