BDBM2575 3-[(2-tert-butylphenyl)sulfanyl]-4-hydroxy-6-(3-methylphenyl)-2H-pyran-2-one::4-hydroxy-6-phenylpyranone 23

SMILES Cc1cccc(c1)-c1cc(O)c(Sc2ccccc2C(C)(C)C)c(=O)o1

InChI Key InChIKey=XOYZMPVCKRRJDK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2575   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM2575(3-[(2-tert-butylphenyl)sulfanyl]-4-hydroxy-6-(3-me...)
Affinity DataIC50: 7nMpH: 4.7 T: 2°CAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2004
Entry Details Article
PubMed